벼랑끝 바이오 매드 컴퓨터 사이언티스트

https://www.biorxiv.org/content/10.1101/2022.07.10.499510v5 Antigen-Specific Antibody Design and Optimization with Diffusion-Based Generative Models for Protein StructuresAntibodies are immune system proteins that protect the host by binding to specific antigens such as viruses and bacteria. The binding between antibodies and antigens is mainly determined by the complementarity-determining regio..

간단 요약 1. 모델이름 : HyperAttentionDTI 2. 저널 : Bioinformatics(IF 6.0 ~ 7.0) 3. Published date : 2022 / 02 4. BenchMark Datasets : DrugBank, Davis, KIBA 5. Main model architectures : Compound : chracterwise Embedding + stacked 1D-CNN Protien : chracterwise Embedding + stacked 1D-CNN Drug-Protein Cross-Attention Global Max Pooling 6. Interaction map idea : simple concatenation btw. drug, prot represent..